| ncRNA name | Miat |
| ncRNA Category | lncRNA |
| ID | 330166 |
| Ensembl | ENSMUSG00000097767 |
| Synonyms | A230057G18Rik, Rncr2, gomafu |
| Disease name | diabetic retinopathy (DR) |
| Species | Mus musculus |
| Tissues/Cell_line | mouse Müller cells |
| Methods | qPCR, Western blot, CHIP, transfection, MTT assay, flow cytometry, luciferase reporter assay |
| Expression pattern | up-regulated |
| Functional description | High glucose stimulation increased the cell apoptosis and decreased the cell activity, while MIAT suppression reversed the effect induced by high glucose, however, miR-29b knockdown reversed the effects induced by MIAT suppression. |
| PubMed ID | 28246353 |
| Year | 2017 |
| Title | Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.